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June 2016

Volume 3 Issue 1

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Case Report 
Wegener’s Granulomatosis with Cardiac İnvolvement

O. Safak MD, E. Gursul MD, M. Polat MD, F. Akcay MD, S. Tuluce MD, F. Aytemiz MD, S. Altay MD, Z. Soypacaci MD

Wegener’s granulomatosis (Granulomatosis with polyangiitis) is a form of vasculitis of small-to-medium sized vessels and associated with diffuse anti-neutrophil cytoplasmic antibodies (cANCA). Cardiac involvement is not uncommon with %6-25 of unsellected patients and up to %44 of patients with severe renal involvement. We report a 23 year-old man with Wegener’s cardiomyopathy with 25% ejection fraction. The overall mortality rate of Wegener’s granulomatosis with cardiac involvement has been reported to be between 15–45%. So it is important to keep in mind that cardiac examination is a must to detect if cardiac involvement is present.

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Research article 

Helicobacter pylori Infection is a Significant Risk Factor for Hyperhomocysteinemia in Patients with Coronary Artery Disease

Soudabeh Falla*, Nariman Moradi, Reza Fadaei, Reza Ahmadi, Azardokht Tabatabei, Morteza Seifi

Cardiovascular disease is the most common cause of mortality and morbidity in the United States and many other nations. Coronary atherosclerosis process is multi-factorial. Traditional and classic cardiovascular risk factors such as diabetes mellitus (DM), hypertension (HTN), smoking and obesity have introduced as major causes, but significant proportions of patients with coronary artery disease (CAD) do not have these traditional risks. Other factors which may affect this chronic process were evaluated.

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