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December 2014

Volume 1 Issue 1  

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Research Article
Prognostic Role of Right Ventricle in Mitral Valve Surgery for Ischemic Mitral Regurgitation

Michele Di Mauro*, Angela L Iaco, Daniela Clemente, Francesca Romana Scopigni, Stefano Guarracini, Silvio Romano, Sabina Gallina, Antonio Maria Calafiore

To evaluate if preoperative right ventricular (RV) dilatation or dysfunction may affect mid-term cardiac mortality of patients with ischemic mitral regurgitation (IMR) undergoing mitral valve surgery (MVS), independently from pulmonary hypertension (PH).                                                                                                     

                                                                                                                                                             Download PDF Full text   

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Editorial

Scombroid Syndrome and Allergic Acute Coronary Events

Egidio Imbalzano*, Matteo Casale, Salvina Quattrocchi, Maria Sergi, Vito Pipitone, Giuseppe Dattilo

Scombroid Syndrome (SS, also known as Scombrotoxism or Scombroid Ichthyotoxicosis) is a recently described pathology due to the consumption of altered fish flesh, in the absence of organoleptic abnormalities. It is a particular type of Kounis Syndrome, a disease in which a cardiovascular event (a coronary vasospasm, a myocardial infarction or a stent thrombosis) occurs as the consequence of an allergic or hypersensitivity, anaphylactic or anaphylactoid insult.                                                                                                     

                                                                                                                                                             Download PDF Full text  ___________________________________________________________________________________________________________________________

Review Article

Thienopyridines, Beyond ADP Antagonism: A Review of Pleiotropic Effects

 Ashish Shah MBBS, MD*, William Chan MBBS, PhD 

Platelet activation is fundamentally involved in the initiation and development of atherosclerotic disease. It orchestrates the triad of inflammation, atherosclerosis and thrombosis. Thienopyrindines are one of the most commonly prescribed drugs for secondary prevention of cardiovascular diseases.                                                                                                     

                                                                                                                                                             Download PDF Full text  ______________________________________________________________________________________

Case Report
Severe Bicuspid Aortic Valve Stenosis, Single Right Coronary Artery and Main Stem-Equivalent Atherosclerosis: A Functional Triad Causing Effort-Induced Syncope

Thomas J Cahill*, Hannah McConkey, Ravi De Silva, Attila Kardos*

Syncope is a common hospital presentation with a broad underlying differential diagnosis. We report a novel functional triad of severe biscuspid aortic stenosis,single right coronary artery and stenosis of the main stem-equivalent in a patient presenting with exercise-induced syncope.                                                                                                     

                                                                                                                                                             Download PDF Full text

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Review Article
Stem Cell-Mediated Medicine for the Cardiovascular Disease

Sung-Whan Kim*, Byeong-Wook Song

Stem cell-based studies have investigated to evaluate the potential of therapeutic effects for the treatment of cardiovascular disease. That is, myocardial and vascular regeneration have been initially proposed as mechanism of action in stem cell biology.                                                                                                     

                                                                                                                                                             Download PDF   Full text____________________________________________________________________________________________

Research Article

Efficacy and Safety of the Novel Sirolimus-Eluting, Biodegradable Polymer Coated Stent in Human Coronary Lesions

Qiu-Ping SHI MD, Ming CHEN, MD*, Hong-Yu PENG, Ph.D, Bin ZHANG, Ph.D, Bo ZHENG, MD, Xin-Gang WANG,MD and Yong HUO, MD

The postulated relationship between nonbiodegradable polymers and LST has led to a concerted effort to seek alternative biodegradable polymers for drug delivery. Bioabsorbable coatings with a degradation period matched to that of the drug elution may be a better alternative, clinically and economically. The purpose of this study was to evaluate the safety and the efficacy of the novel sirolimus-eluting stent (SES) with biodegradable polylactic-co-glycolic acid (PLGA) polymeric matrix (Tivoli™, Essen Technology, Beijing, China) implantation in human atherosclerotic coronary.                                                                                                     

                                                                                                                                                             Download PDF  Full text

 

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